Stem cell injection for long-term low back pain
Part of Bones, joints & muscles clinical trials.
This trial tests a new stem cell injection (CELZ-201-DDT) into a muscle to treat chronic lower back pain that hasn't improved with standard treatments. It aims to see if the injection is safe and effective for people aged 18 to 80 with moderate to severe back pain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You have tried at least two standard treatments (like physical therapy, painkillers, or muscle relaxants) for at least 3 months each, and they didn't work.
- You have evidence of disc degeneration on an MRI, or a back pain disability score of 21-80%, or a pain score above 5 out of 10.
- You do not have a history of cancer in the last 5 years, active infections, serious kidney or liver problems, uncontrolled diabetes or high blood pressure, or a body mass index (BMI) over 40.
- You are willing to use birth control during the study (if applicable) and not pregnant or breastfeeding.
- You have not had gene therapy in the past or used an experimental drug in the last 30 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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