Testing a new gene therapy for chronic low back pain
Part of Bones, joints & muscles clinical trials.
This trial tests a new gene therapy called TG-C for people with chronic low back pain caused by degenerative disc disease. The goal is to see if it is safe and tolerable, and it might offer a new treatment option for those who haven't found relief from other therapies.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 22 and 70 years old.
- You have had low back pain for at least 6 months, and your back pain is twice as bad as any leg pain.
- You have tried at least one pain medication (like ibuprofen or Tylenol) and physical therapy without enough relief.
- An MRI has confirmed you have degenerative disc disease in your lower spine.
- You are not pregnant and agree to use birth control during the study.
- Your body mass index (BMI) is between 15 and 30.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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