Study of anakinra for advanced heart failure on inotrope therapy
Treatments studied
Part of Digestive system, Heart & circulation, Infections clinical trials.
This study tests whether a drug called anakinra can improve how your heart responds to inotrope therapy (medicines that help your heart pump). It is for people with advanced heart failure who are already on a steady dose of these medicines and have signs of inflammation. The goal is to see if blocking inflammation helps your heart work better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have advanced heart failure (stage D) and have been on a steady dose of an inotrope medicine (dobutamine or milrinone) for at least 28 days.
- You have had no hospital stays in the last month.
- You are 21 years or older and willing to sign a consent form.
- Your blood test shows a C-reactive protein level above 2 mg/L (a sign of inflammation).
- You do not have other serious health issues like active infections, recent heart surgeries, or cancer treatments.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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