Study drug effect on heart muscle calcium in advanced heart failure
Part of Heart & circulation clinical trials.
This trial tests a treatment intended to improve how heart muscle cells handle calcium, which may help heart failure symptoms and heart function. It is mainly for people with advanced heart failure and a low pumping strength of the heart.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have chronic heart muscle disease from either blocked heart arteries or other non-blocked causes
- Your heart failure is advanced (NYHA class III or IV)
- Your heart’s pumping strength is low (left ventricular ejection fraction of 35% or less)
- You are already on standard heart failure medicines, and you have an ICD (implantable defibrillator)
- You do not have certain other heart muscle/scar conditions (like restrictive or hypertrophic cardiomyopathy, amyloidosis, or an infiltrative cause)
- You have not had certain heart procedures/devices recently and do not expect major heart procedures within 6 months
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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