Using DNA sequencing to find infections in fever patients with low white blood cells
Part of Blood & lymphatic, Infections clinical trials.
This study tests a new DNA sequencing method to identify infections in cancer patients who have a fever and very low white blood cells (neutropenia). It may help doctors find the cause faster and choose the right treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are being treated for a solid tumor or blood cancer.
- You have a fever (temperature of 38.3°C or higher, or 38°C twice within an hour) with low white blood cells (under 500/mm³).
- Your low white blood cell count is expected to last 7 days or more.
- You have not taken antibiotics in the last 24 hours (except for certain preventive antibiotics like Cotrimoxazole or Oracillin®).
- You agree to participate and can provide consent.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies whether advanced genetic testing (next-generation sequencing) can help doctors better understand and manage neutropenic sepsis—a serious infection risk when white blood cell counts are too low. You may be considered if you develop fever or sepsis quickly (within 24 hours) while your counts are low.
This trial studies whether proteins in your blood can predict complications when you have a fever and very low white blood cells after cancer treatment. It aims to help doctors choose the best antibiotics early on.
This study tests whether analyzing stool and urine samples using advanced genetic technology can identify infections causing unexplained illness in people with weakened immune systems. The goal is to find infections faster and help doctors treat them more effectively.
This study tests whether adults with “high-risk febrile neutropenia” can safely get a shorter course of antibiotics. It may help reduce side effects from antibiotics while still keeping infections under control.
This study looks at how long antibiotics should be given to cancer patients with fever and very low white blood cell counts after finding a certain type of bacteria (Gram-negative) in their blood. The goal is to find the best treatment duration to help patients recover without complications.
This study tests whether a sensitive blood test can find hidden fungal infections in people with blood cancers. It may help your doctor start the right treatment sooner.
Hear when a new Immunodepressed Patients (Hemato-oncology) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.