Shorter antibiotics for high-risk fever with low white blood cells
Part of Blood & lymphatic, Infections clinical trials.
This study looks at how long antibiotics should be given to cancer patients with fever and very low white blood cell counts after finding a certain type of bacteria (Gram-negative) in their blood. The goal is to find the best treatment duration to help patients recover without complications.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a blood cancer (like leukemia or lymphoma) and are getting chemotherapy, a bone marrow transplant, or CAR-T cell therapy.
- You currently have a fever (temperature at least 38.3°C once or 38.0°C for an hour) with very low white blood cells (under 1000 cells per microliter of blood).
- Your low white blood cell count is expected to last at least 7 days.
- You have a confirmed infection in your blood caused by Gram-negative bacteria.
- You do not have pneumonia or a serious belly infection like typhlitis.
- You are not still having positive blood cultures after starting antibiotics.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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