Ultrasound brain stimulation for hard-to-treat depression
Part of Mental health clinical trials.
This trial tests whether a gentle ultrasound treatment aimed at the brain can help people with severe depression that hasn't improved with at least two prior medications. It's a first small study to see if the approach is safe and promising.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You currently have severe major depression (scoring high on a depression rating scale).
- You have tried at least two different antidepressant treatments that did not work well enough.
- You have been on a stable antidepressant dose for at least 4 weeks before starting.
- You do not have other major psychiatric or neurological conditions (like epilepsy or a brain injury).
- You are willing and able to have an MRI scan (no metal implants or pacemaker).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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