Probiotics to prevent pneumonia in ventilated patients
Part of Brain & nervous system, Heart & circulation, Infections, Injuries & trauma, Lungs & breathing clinical trials.
This trial tests whether giving probiotics to patients on a breathing machine (mechanical ventilation) can help prevent pneumonia. It is for adults who are on a ventilator after a recent head injury, stroke, or brain bleed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 18 and 80 years old
- Have a recent head injury (with other injuries) or a stroke/brain hemorrhage without signs of lung infection
- Started on a breathing machine (ventilator) immediately after the event, within hours
- Expected to need the breathing machine for at least 6 days
- Not pregnant or breastfeeding
- Not have a weak immune system from HIV, certain medications, or recent cancer treatment
- Not have severe pancreatitis, ischemic bowel disease, or mouth/throat injury
- Not have certain heart valve problems, endocarditis, or permanent heart devices like pacemakers
- Not have sepsis or septic shock
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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