Microbiome-guided treatment to prevent lung infection in ICU patients on ventilators
Part of Infections, Lungs & breathing clinical trials.
This study tests whether giving inhaled antibiotics based on a patient's own airway bacteria can prevent ventilator-associated pneumonia (a lung infection from the breathing tube) in intensive care patients. It may help reduce infections in people who need a breathing tube for more than three days.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older and in the intensive care unit (ICU).
- You are on a breathing tube (ventilator) and are expected to need it for more than 72 hours.
- You do not have any form of pneumonia (lung infection) now.
- You do not have severe chronic lung disease that requires home oxygen or a home ventilator.
- You have not had a tracheostomy (a tube directly in your windpipe through your neck).
- You are not pregnant.
- You have not been on the ventilator for more than 48 hours before joining.
- You are not taking part in another trial for antimicrobial or immune-modulating drugs.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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