Using gut bacteria to prevent pneumonia in ICU patients on ventilators
Part of Infections, Lungs & breathing clinical trials.
This trial tests if giving antibiotics based on a patient's unique gut bacteria can prevent pneumonia in people who are on a breathing machine (ventilator) in the intensive care unit (ICU). It aims to see if this personalized approach is more effective than standard care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older and admitted to the ICU at Foothills Medical Centre.
- You are on a breathing machine (ventilator) with a tube in your windpipe.
- Your doctor expects you will need the breathing machine for more than 3 days.
- You do not have pneumonia when starting the study.
- You do not have severe chronic lung disease that requires home oxygen or a home breathing machine.
- You are not allergic to the antibiotics used in the study (tobramycin, aztreonam, or vancomycin).
- You have been on the breathing machine for less than 48 hours.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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