Anlotinib plus Aumolertinib for first-line treatment of advanced EGFR-mutant lung cancer
Part of Cancer, Lungs & breathing clinical trials.
This trial tests a combination of two targeted drugs (anlotinib and aumolertinib) as the first treatment for advanced lung cancer with a specific EGFR mutation (L858R). The goal is to see if the combination works better than standard care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have advanced non-small cell lung cancer (stage IIIB, IIIC, or IV) that cannot be removed by surgery.
- Your cancer has the EGFR L858R mutation (a specific change in the EGFR gene).
- You have not had any previous cancer treatment, including chemotherapy, radiation, targeted therapy, or immunotherapy.
- You have at least one tumor that can be measured on scans.
- You are 18 years or older and able to care for yourself (ECOG score 0–3).
- Your blood counts, liver, and kidney function are within certain limits.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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