How opioid addiction meds affect sleep and eyes
Part of Brain & nervous system, Mental health clinical trials.
This study tests how three common medications for opioid use disorder (methadone, buprenorphine, and naltrexone) affect eye function, sleep, and daily body rhythms. It may help find ways to improve treatment for opioid addiction.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older
- You are prescribed methadone, extended-release naltrexone (a shot), or buprenorphine for opioid use disorder and have been on a steady dose for at least a month, OR you are a healthy person not taking these meds
- If you are taking buprenorphine or methadone, a urine drug test must show the medication is in your system
- You do not have any eye disease (like cataracts, glaucoma, or macular degeneration) and have not had eye surgery that might affect the study
- You have not used any illegal opioids, stimulants (even prescribed ones like Adderall), or benzodiazepines in the past month
- You do not work night shifts (outside 7 a.m. to 6 p.m.) and do not have narcolepsy
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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