Comparing hyaluronic acid to enamel matrix for gum regrowth
Treatments studied
Part of Mouth & dental clinical trials.
This trial tests whether a gel made from hyaluronic acid helps rebuild bone and gum tissue around teeth as well as a standard treatment (enamel matrix derivative). It's for people with advanced gum disease who have completed initial cleaning and still have deep pockets that need repair.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have stage III or IV gum disease.
- You've already finished steps 1 and 2 of gum treatment (like deep cleaning).
- Your mouth has less than 15% bleeding and plaque at a checkup 3 months after treatment.
- You have at least one tooth with a deep pocket (6 mm or more) and bone loss of 3 mm or more, visible on x-ray.
- The damaged area must be reachable during surgery from only one side (front or back) and have a certain bone shape.
- You are not a heavy smoker (10+ cigarettes a day), don't use chewing tobacco, and aren't pregnant or nursing.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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