Clin2
NCT06105762Possibly a fitNot yet recruiting

Ketogenic diet for depression

Depressive DisorderMajor Depressive DisorderDepression, Bipolar

Part of Mental health clinical trials.

This study tests whether a ketogenic diet (a high-fat, low-carbohydrate diet) can improve symptoms of depression. It is a dietary intervention that may help your mood, but it requires commitment to following the diet and avoiding alcohol and other substances during the study.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
120 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You must have a clear diagnosis of major depression or bipolar depression.
  • You must be at least 18 years old.
  • You need to be interested in trying a special high-fat, low-carbohydrate diet (called a ketogenic diet).
  • You must agree not to use any non-prescribed substances (including alcohol, cannabis, or other drugs) during the study.
  • You cannot take part if you have certain health conditions, such as type 1 diabetes, insulin-dependent type 2 diabetes, pancreatitis, or severe heart, liver, kidney, or lung disease.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06748950Not yet recruiting
Ketogenic diet study for mood and psychotic disorders

This study tests whether a ketogenic diet (a high-fat, low-carbohydrate diet) can help people with bipolar disorder, major depression, or schizophrenia. The diet may improve symptoms by changing how the body and brain use energy.

Palo Alto, California
NCT07002684Recruiting
Esketamine study for depression

This trial tests how treatment with esketamine affects metabolism in people with depression. It may help if you have not responded to at least two standard antidepressants.

Zagreb
NCT07399756Not yet recruiting
How ketamine affects energy in cells for treatment-resistant depression

This study looks at how ketamine, a fast-acting treatment for severe depression, affects the energy-producing parts of cells (mitochondria). If you qualify, you'll help researchers understand why ketamine works, which could lead to better depression treatments.

Ramat Gan, Israel
NCT06559826Recruiting· Phase 2
Ketamine therapy with or without talk for depression

This study compares ketamine alone to ketamine combined with psychotherapy for treating depression. It may help if you have moderate to severe depression and want to see if adding talk therapy improves results.

New York, New York
NCT07121894Recruiting
Ketogenic diet for bipolar depression

This study tests whether a strict low-carbohydrate, high-fat (ketogenic) diet can improve symptoms of depression in people with bipolar disorder. Participants will receive dietary guidance and support to help them follow the diet for several weeks.

Rochester, Minnesota
NCT06221852Recruiting
Ketogenic diet for first episode bipolar disorder

This study tests whether a special high-fat, low-carbohydrate diet (ketogenic diet) can help people who have recently been diagnosed with bipolar disorder. It may improve mood stability and overall brain health.

Belmont, Massachusetts

Hear when a new Depressive Disorder trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.