Testing the MRace implant for leaky heart valve repair
Part of Heart & circulation clinical trials.
This trial tests a new device called MRace that may fix a leaky mitral valve without open-heart surgery. It's for people whose valve leaks severely and who can't have standard surgery due to other health issues.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older.
- Your mitral valve leak must be severe (grade 3+), confirmed by an ultrasound within the last 3 months.
- Your surgical risk score must be low enough (under 10%), but you still can't have standard surgery because of things like calcium buildup in the valve.
- You should be in heart failure with symptoms like shortness of breath or fatigue even at rest or with light activity.
- You must be able to attend follow-up visits for at least 1 year.
- You cannot have other serious heart valve problems, blood clots, active infections, or recent strokes.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how safe and effective a specific catheter procedure is for people with moderate-to-severe mitral valve leakage. It may help those who are considered high risk for traditional open-heart surgery.
This study tests a new device called MRace that is placed through a vein in the leg to fix a leaky mitral valve (the valve between the upper and lower left heart chambers). It is for people who have significant leakage and whose heart anatomy does not allow the usual clip repair. The goal is to see if the MRace can safely and effectively reduce the leak and improve symptoms.
This study tests a new device called MRace that is placed through a vein in the leg to fix a leaky mitral valve in people whose valve shape is not suitable for the usual repair. It is for patients with heart failure and moderate-to-severe regurgitation who are still able to have surgery but are considered high risk.
This study tests a new device, MRace, for people with severe functional mitral regurgitation, a condition where the heart's mitral valve doesn't close fully, causing blood to leak backward. The trial is for patients who have unusual heart structures that make the standard clip procedure difficult. The goal is to see if MRace can safely and effectively fix the leak and improve symptoms.
This trial tests a new device called the Capstan system to fix a leaky mitral valve (mitral regurgitation) without open-heart surgery. It may help people whose valve leak is moderate to severe and still have symptoms despite medicines.
This trial tests a new device designed to fix a leaky mitral valve in people with heart failure. It may help you breathe easier and feel less tired if your valve leak is severe and medicines have not been enough.
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