MRace device for mitral regurgitation when standard treatment isn't possible
Part of Digestive system, Heart & circulation clinical trials.
This study tests a new device (MRace) for people with a leaky mitral valve whose anatomy is too complex for the standard clip treatment. The device is placed through a vein in the leg to help the valve close better, which may reduce symptoms and improve quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have moderate-to-severe or severe functional mitral regurgitation – a leaky heart valve that causes symptoms like breathlessness or tiredness despite taking heart medications.
- Your heart team has determined that the standard clip procedure (M-TEER) won't work well for your valve shape.
- You are 21 years or older and considered high risk for open heart surgery, but could have surgery if needed.
- Your heart function is not too weak (ejection fraction above 30%) and your heart size is within certain limits.
- You have at least one complex feature of your valve anatomy, like a large opening, calcium buildup, or a specific leaflet issue.
- You have not had prior mitral valve surgery or a transcatheter mitral valve procedure, and you don't have severe disease of other heart valves.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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