GlycOrtho: Endothelial damage in major spine surgery
Part of Bones, joints & muscles clinical trials.
This study looks at how major spine surgery affects the inner lining of blood vessels. It measures a substance called syndecan-1 in the blood to understand this damage.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are scheduled for major spine surgery where blood loss is expected to be more than 25% of your total blood volume.
- Your health status is classified as ASA 1, 2, or 3.
- You can understand and sign a consent form. If you are under 18, a parent or legal guardian can do this.
- Your surgery is not for a genetic syndrome or neuromuscular scoliosis.
- Your surgery is scheduled during laboratory working hours.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial looks at how certain markers of bone and muscle health might predict complications after spinal surgery. It could help doctors better understand which patients are at risk and improve recovery.
This study follows patients of any age who are having a minimally invasive procedure (endovascular treatment) for blood vessel problems in the brain or spine. It looks at how patients do before and after the procedure, any complications, and what factors might predict a good outcome.
This trial looks at how a protective layer inside your blood vessels (called the glycocalyx) responds during surgery to remove burned skin. The goal is to improve care for people with major burns.
This study looks at genetic (inherited) factors that may influence bone healing in people undergoing major spine procedures. It may help researchers understand why some people heal differently and could guide better care in the future.
This trial tests whether collecting your blood during surgery and giving it back to you afterward is safe and helpful for large spine surgeries. It is for adults with specific types of severe spine curves or who need extensive back surgery.
This study checks blood and other lab “biomarkers” during the time before and after major surgeries to see if they can help guide perioperative care. You might be eligible if you are having certain planned heart, lung, GI, or blood-vessel surgeries and can give informed consent.
Hear when a new Spinal Fusion trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.