Ablation for AFib in patients with heart failure and preserved ejection fraction
Treatments studied
Part of Heart & circulation clinical trials.
This study tests whether a catheter ablation procedure can help people with atrial fibrillation and a kind of heart failure where the heart pumps normally but doesn't relax properly (HFpEF). It looks at whether the procedure can improve symptoms and heart function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have atrial fibrillation (AFib) that comes and goes (paroxysmal) or stays for a while (persistent).
- You have a heart failure diagnosis called HFpEF, meaning your heart's pumping strength is normal (LVEF ≥ 50%) but you have symptoms like shortness of breath or fluid buildup.
- Your NT-proBNP level (a heart stress marker) is above 300 while in normal rhythm, or above 600 while in AFib.
- You have an ultrasound showing your heart's relaxation is impaired.
- You are not eligible if you've had AFib ablation before, your left atrium is very large (≥ 55 mm), or you have other serious heart conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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