Clin2
NCT06740539Possibly a fitNot yet recruiting

Catheter ablation vs. rhythm drugs for atrial fibrillation with heart failure

HFpEF - Heart Failure with Preserved Ejection FractionAtrial Fibrillation (AF)

Part of Heart & circulation clinical trials.

This study compares two treatments for people with atrial fibrillation (an irregular heartbeat) and a specific type of heart failure. It looks at whether a procedure called catheter ablation (which uses heat to fix the heart's rhythm) works better than taking daily heart rhythm medications.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
304 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • You have atrial fibrillation (an irregular heartbeat) that is either occasional or constant.
  • You have heart failure with preserved ejection fraction (a type of heart failure where the heart's pumping ability is normal but it is stiff).
  • Heart rhythm medications have not worked for you, caused side effects, or you prefer not to take them.
  • You have not had a prior ablation (a procedure to scar heart tissue) on the left side of your heart.
  • You have not had a heart attack, heart surgery, angioplasty, or stroke in the last 2 months.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07077811Enrolling by invitation
Pulsed field ablation for heart failure with preserved pumping strength

This trial tests a new procedure called pulsed field ablation for people who have both persistent atrial fibrillation and a type of heart failure (HFpEF). It aims to see if this ablation safely helps control the heart rhythm.

Nantong, Jiangsu
NCT06505798Recruiting
Ablation vs medication for heart failure with atrial fibrillation

This trial compares a procedure called ablation (using cold, heat, or electric pulses to fix irregular heartbeats) with standard medications to see which better treats heart failure in people who also have atrial fibrillation. It may help if your heart's pumping ability is reduced and you still have symptoms despite medications.

Halifax
NCT07272902Recruiting
Atrial fibrillation treatment: Ablation vs. medication

This trial compares two ways to treat atrial fibrillation in people with heart failure where the heart's pumping strength is still normal. You'll either get a procedure called ablation to restore normal rhythm or medication to control your heart rate. The goal is to see which approach works better for people like you.

Halifax, Nova Scotia
NCT06125925Recruiting
Ablation for AFib in patients with heart failure and preserved ejection fraction

This study tests whether a catheter ablation procedure can help people with atrial fibrillation and a kind of heart failure where the heart pumps normally but doesn't relax properly (HFpEF). It looks at whether the procedure can improve symptoms and heart function.

Nanjing
NCT07238452Not yet recruiting· Phase 3
Comparing treatment options for atrial fibrillation in people with heart failure

This study compares two different treatment strategies for atrial fibrillation (an irregular heartbeat) in people who also have heart failure. One strategy uses medications only, while the other includes a procedure to restore normal heart rhythm. The goal is to find the best way to improve symptoms and outcomes.

NCT06866704Not yet recruiting
Comparing two ablation methods for persistent atrial fibrillation

This study compares two procedures to treat persistent atrial fibrillation (an irregular heartbeat that lasts more than a week). It looks at whether a newer method (pulsed-field ablation) works better than the standard method (radiofrequency ablation), both combined with a chemical injection to improve treatment success.

Hear when a new HFpEF - Heart Failure with Preserved Ejection Fraction trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.