Colchicine and vitamin B1 for ischemic heart failure
Treatments studied
Part of Heart & circulation clinical trials.
This study tests whether colchicine and thiamine (vitamin B1) can improve outcomes in people with heart failure caused by blocked or narrowed heart arteries. It’s mainly for people with moderate-to-severe symptoms and reduced heart pumping ability.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 45 or older
- Your heart failure is due to ischemic heart disease (blocked/narrowed heart arteries), based on your doctor’s assessment
- Your heart failure symptoms are New York Heart Association (NYHA) class II, III, or IV
- Your heart’s pumping strength (LVEF) is 45% or less within the past year
- You are on your usual heart failure medicines at the right doses for you (optimized treatment)
- If you are currently in the hospital, you must be stable and likely to be discharged within 72 hours
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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