Study of ENA-001 for breathing problems after surgery
Part of Lungs & breathing clinical trials.
This trial tests a new medicine, ENA-001, to treat breathing difficulties that can happen after major surgery. It may help you recover more safely from anesthesia and painkillers.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are scheduled for a major elective surgery (like abdominal, laparoscopic, kidney, chest, shoulder, or ankle surgery) and will recover in the general recovery room.
- You need at least 250 micrograms of fentanyl during surgery for pain.
- You are 18 years or older and in generally good health (classified as ASA 1-3).
- You have no heart problems, and your heart test (ECG) is normal.
- Your vital signs (temperature, blood pressure, pulse) are within normal ranges at screening and on the day of treatment.
- If you are of childbearing potential, you must agree to use effective birth control or be abstinent during the study and for 3 months after.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new medicine (ENA-001) that helps restore normal breathing when it has slowed down too much due to opioid painkillers. Healthy volunteers will receive the drug to see how safe it is and how the body handles it.
This trial tests two different pain medicines, nalbuphine and fentanyl, to see which one causes fewer changes in blood pressure and heart rate during the placement of a breathing tube for heart surgery.
This trial looks at whether people’s anxiety before ear, nose, and throat (ENT) surgery affects how much pain medicine (opioids) they need after surgery. It may help doctors better plan pain control based on anxiety level and possibly gender-related patterns.
This trial tests a computer system that controls anesthesia during routine painless gastrointestinal endoscopy. The system learns from past procedures to keep you safely asleep while the doctor examines your digestive tract.
This study tests a new way to give anesthesia during painless upper and lower GI exams by using a special monitor that tracks your body's response to pain. The goal is to make the procedure more comfortable and safer for you.
This trial studies a “closed-loop” anesthesia delivery system that automatically adjusts anesthesia during surgery. It may help by making anesthesia more consistent and safer while you’re undergoing planned non-heart surgery.
Hear when a new Respiratory Depression trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.