Clin2
NCT06143579Possibly a fitNot yet recruiting

Combination therapy for liver cancer that can be surgically removed

Potentially Resectable Hepatocellular Carcinoma

Part of Cancer clinical trials.

This trial tests a combination of three treatments—chemo given directly into the liver, an oral targeted therapy, and an immunotherapy—for people with liver cancer that could be removed by surgery but isn't the first choice right now. The goal is to see if this combination can shrink the tumor and improve outcomes before surgery.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
48 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have been diagnosed with hepatocellular carcinoma (a type of liver cancer) that has not spread to other parts of the body.
  • Your liver cancer is considered potentially removable by surgery, but surgery is not the first choice right now (for example, the tumor is large or involves certain blood vessels).
  • You have not been previously treated with a PD-1 inhibitor (a type of immunotherapy) or lenvatinib (a targeted therapy).
  • You are generally in good health, with a performance status of 0 or 1 (able to do daily activities without major help).
  • Your liver function is adequate (Child-Pugh score of 7 or less, and no severe cirrhosis).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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