Mitral valve elasticity study during replacement

This trial focuses on people with severe mitral valve narrowing or leaking who still have symptoms even after the best usual medications. It may help find better care and measure health outcomes when surgery is judged too risky or not suitable.

This study keeps a registry of adults who have a mitral valve problem and are being evaluated for a catheter-based mitral valve replacement. It helps doctors understand what treatments are used and how patients do.

This study collects and compares real-world results to help doctors choose the best treatment for mitral valve “leakiness.” If you have clinically significant mitral insufficiency and have already had a specific heart procedure screening, your echocardiogram results may be used to understand outcomes over at least a month.

This trial compares two surgical techniques for replacing the mitral valve. One technique keeps more of the natural supporting structures (the subvalvular apparatus) than the other. The goal is to find out which approach gives better heart function and quality of life after surgery.

This study looks at people who had their mitral valve replaced to see if the original valve problem (tight vs leaky) affects how long the new valve lasts. It may help doctors understand which patients need closer follow-up.

This trial is testing a replacement valve (called MITRIS) for people whose own mitral valve or a previous artificial valve is not working well. The goal is to see how well the valve works over time after it is implanted.