Clip repair for severe mitral valve leak
Part of Heart & circulation clinical trials.
This trial tests a clip-based procedure (TEER) to fix a severe leak in the mitral valve for people who have symptoms or heart changes but are at low to medium risk for surgery. The goal is to see if this less invasive option works well and is safe.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have a severe mitral valve leak (grade 3+ on an ultrasound test)
- You have symptoms like shortness of breath, fatigue, or swelling, or your heart is showing signs of stress on tests
- A heart team has reviewed your case and says surgery is an option but your risk from surgery is low to medium
- You agree to take part and come back for checkups for at least 1 year
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether using only ultrasound (echo) to guide a mitral valve clip repair is as good as using ultrasound plus X-ray. The study may help patients with a leaky mitral valve who are not good candidates for open heart surgery.
This trial tests Valveclip, a catheter-based way to repair a mitral valve that is leaking badly. It may help people who are high-risk for open surgery by aiming to reduce the leak with a less invasive approach.
This study tests a new clip procedure (CardioClip) to repair a leaky mitral valve in people with heart failure. It aims to see if the clip can improve symptoms and heart function.
This trial studies whether a device called GeminiOne can safely and effectively repair a leaky mitral valve using a catheter-based “clip” technique. It may help patients who have moderate-to-severe or severe valve leakage but are considered too high-risk for open surgery.
This trial tests a new device called the Capstan system to fix a leaky mitral valve (mitral regurgitation) without open-heart surgery. It may help people whose valve leak is moderate to severe and still have symptoms despite medicines.
This study is testing a new assist system to help doctors perform a minimally invasive procedure (MitraClip) that clips the leaky mitral valve without open-heart surgery. It is for people with severe mitral regurgitation who cannot safely have surgery or choose not to.
Hear when a new Mitral Regurgitation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.