Saliva test for heart failure diagnosis
Part of Heart & circulation clinical trials.
This study tests whether a simple saliva sample can detect certain molecules (lncRNAs) that might help diagnose heart failure. It looks at two types of heart failure: chronic stable heart failure and acute decompensated heart failure, and compares them to people without heart failure who are having a heart procedure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have either chronic stable heart failure (CHF) or acute decompensated heart failure (ADHF).
- If you have CHF, you have symptoms that limit activity (NYHA class II, III, or IV) and a specific blood test (NT-proBNP) level that matches your heart's pumping strength.
- If you have ADHF, you have symptoms (like shortness of breath or leg swelling) and meet certain blood test or physical exam criteria.
- You are not pregnant, do not have cardiac amyloidosis, and do not have an active cancer.
- You are not currently breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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