Clin2
NCT06195618Possibly a fitNot yet recruiting

Personalized vaccine for triple-negative breast cancer

Breast Cancer Female

Part of Cancer, Skin clinical trials.

This trial tests a personal vaccine made from your own tumor's unique markers (neoantigens) to help your immune system fight triple-negative breast cancer. It's for people who've already had standard treatment and whose tumor markers can be matched to a custom vaccine.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
8 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old.
  • You have been diagnosed with triple-negative breast cancer (a type that doesn't have the usual hormone receptors).
  • You have already received standard treatment (like chemo, radiation, or surgery).
  • Your tumor's unique markers (called neoantigens) have been found and a custom vaccine made from them can be created.
  • You are healthy enough: your daily activity level is at 70% or better on a standard scale.
  • You are not pregnant or breastfeeding, and don’t have serious heart, kidney, or bleeding problems.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06435351Recruiting· Early Phase 1
Personalized vaccine for high-risk triple-negative breast cancer

This trial tests a personalized vaccine made from your own immune cells (dendritic cells) to help prevent your high-risk triple-negative breast cancer from coming back. It is for people who had significant tumor left after standard chemotherapy and surgery.

Tampa, Florida
NCT07300475Not yet recruiting· Phase 1
Personalized vaccine for triple negative breast cancer

This trial tests a personalized cancer vaccine for triple negative breast cancer. It is given alongside standard chemotherapy and immunotherapy to help your immune system fight the cancer.

St Louis, Missouri
NCT06631092Recruiting· Phase 1/Phase 2
Personalized cancer vaccine with standard therapy for triple-negative breast cancer

This trial tests a personalized cancer vaccine (NECVAX-NEO1) given along with standard chemotherapy and immunotherapy before surgery for patients with triple-negative breast cancer. The vaccine is customized to target specific mutations in your tumor, aiming to boost your immune system and improve treatment outcomes.

Erlangen
NCT06324240Recruiting· Phase 1
Personalized vaccine plus immunotherapy for triple-negative breast cancer

This trial tests a personalized vaccine made from your tumor combined with immunotherapy drugs (pembrolizumab or ipilimumab) for triple-negative breast cancer. It aims to help your immune system recognize and attack cancer cells.

Atlanta, Georgia
NCT05475106Recruiting· Early Phase 1
Personalized vaccine using tumor peptide targets and an immune booster

This early-phase trial tests a personalized immune treatment made from your tumor’s specific “neoantigen” targets (small pieces the immune system can recognize), plus an immune-boosting medicine. It aims to help control certain cancers by training your immune system to attack your tumor.

Tijuana, Estado de Baja California
NCT05098210Recruiting· Phase 1
Personalized vaccine made from your tumor’s new immune targets

This Phase 1 study tests a customized vaccine made from “neo-antigens,” which are new targets found in your tumor. It aims to help your immune system fight certain advanced cancers that have not responded well to prior treatment.

Seattle, Washington

Hear when a new Breast Cancer Female trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.