Preventing heart damage from chemotherapy in lymphoma
Treatments studied
Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy, Injuries & trauma clinical trials.
This trial tests if the drug dexrazoxane can protect the heart during chemotherapy for a type of lymphoma called DLBCL. It may be an option for patients starting a standard treatment regimen known as R-CHOP.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a confirmed diagnosis of one of these lymphomas: DLBCL, high-grade B-cell lymphoma, follicular lymphoma, or T-cell/histiocyte-rich B-cell lymphoma.
- You must be starting a treatment plan of 6 cycles of R-CHOP21 (with or without lenalidomide or extra rituximab).
- You must be at least 18 years old.
- Your cancer must be stage II, III, IV, or stage I with a large tumor (10 cm or more).
- You must have adequate organ function (heart, lungs, liver, kidneys) and not have certain other cancers or uncontrolled infections.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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