Dexrazoxane to help protect the heart during blood-cancer chemo
Part of Blood & lymphatic, Cancer clinical trials.
This Phase 2 study tests dexrazoxane, a heart-protecting medicine, to reduce heart side effects from chemotherapy in people with certain blood cancers. If you qualify, you would receive dexrazoxane along with chemotherapy, and the team will monitor your heart function closely.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your heart pumping strength (ejection fraction) must be at least 50% on an echocardiogram or MUGA scan
- You must not be pregnant, and you must use reliable birth control during the study (and avoid breastfeeding)
- You must have one of these blood cancers or related subtypes, such as AML or high-risk MDS, or certain advanced/“blast phase” forms of other blood cancers
- Your liver and kidney blood tests must meet limits (and bilirubin only allowed in some cases like Gilbert’s syndrome)
- You must not have major/unstable heart problems, such as recent heart attack, unstable chest pain, severe rhythm problems, or severe valve disease
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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