Psilocybin for cannabis use disorder
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This trial tests whether a single dose of psilocybin (a psychedelic compound) can help people with moderate to severe cannabis use disorder reduce or stop their cannabis use. You will receive the drug in a supervised setting and have follow-up check-ins.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 65 years old.
- You have been diagnosed with moderate or severe cannabis use disorder and want to cut down or quit.
- You are generally healthy (no serious heart, liver, or kidney problems) and not pregnant or nursing.
- You have not used psychedelics like psilocybin or LSD in the past year, and have used them less than 5 times in your life.
- You are not currently taking certain medications like stimulants, antipsychotics, or benzodiazepines (SSRIs are okay if stable).
- You can speak and read English, have a stable home, and can have someone stay with you overnight after the dosing sessions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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