Pembrolizumab plus lenvatinib or chemo for advanced bile duct cancer
Treatments studied
Part of Cancer clinical trials.
This study tests whether adding another drug (lenvatinib or chemotherapy) to the immunotherapy drug pembrolizumab works better than pembrolizumab alone for advanced bile duct or gallbladder cancer that has not been treated before. It aims to find a more effective first treatment option.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have advanced bile duct or gallbladder cancer that cannot be surgically removed or has spread.
- You cannot have received any previous systemic treatment (like chemotherapy) for advanced cancer.
- Your overall health should be good, with an ECOG score of 0 or 1 (able to do daily activities).
- Blood tests and liver/kidney function must meet certain levels (your doctor will check).
- You cannot have active autoimmune disease, serious heart disease, bleeding issues, or brain metastases that are not under control.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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