Metformin for knee osteoarthritis: a phase 3 trial
Part of Bones, joints & muscles clinical trials.
This study tests whether metformin, a common diabetes medication, can help reduce pain and improve knee function in people with knee osteoarthritis. It may offer a new treatment option for those with moderate knee OA.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 30 and 60 years old.
- You have knee osteoarthritis (grade II or III on X-ray).
- You do NOT have other types of arthritis (like rheumatoid arthritis) or gout.
- You have no recent stomach, liver, or kidney problems.
- You have not had a steroid injection in your knee in the last 8 weeks.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a painless electrical patch that delivers metformin through the skin can reduce knee pain and improve function in postmenopausal women with knee osteoarthritis. If you have moderate knee arthritis and are not currently taking metformin, this might be an option for you.
This trial tests if metformin, a common diabetes drug, can help people with gout. It aims to see if the drug is safe and effective for reducing gout symptoms.
This trial tests whether a common diabetes drug (metformin) combined with exercise and a healthy diet can help people with knee osteoarthritis who are overweight.
This study tests whether metformin, a common diabetes medication, can reduce pain in hand osteoarthritis. You may be eligible if your hand pain is moderate to severe and you haven't taken metformin before.
This study tests whether vitamin D combined with omega-3 or metformin can help with knee osteoarthritis pain. It aims to see if these supplements can reduce pain and improve knee function.
This trial tests whether metformin, a common diabetes medicine, can prevent arthritis after an ACL injury. If you are planning to have ACL surgery soon, you may be able to join.
Hear when a new Osteo Arthritis Knee trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.