JY231 cell therapy for severe autoimmune diseases
Treatments studied
Part of Immune system & allergy clinical trials.
This early-phase trial tests a new cell therapy called JY231 for people with severe autoimmune diseases like lupus, Sjogren's, scleroderma, dermatomyositis, or ANCA vasculitis that haven't improved with standard treatments. It aims to see if the therapy can help control the disease when other options have failed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old
- You have lupus, Sjogren's, systemic sclerosis, dermatomyositis, or ANCA vasculitis that has not responded well to at least 2 standard treatments or needs high-dose steroids
- Your disease is active (meeting specific score criteria for your condition)
- Your major organs (heart, lungs, liver, kidneys, blood) are functioning adequately
- You have not had CAR-T therapy before
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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