Clin2
NCT06251310Possibly a fitRecruiting

Testing SW-682 in Advanced Solid Tumors

Advanced Solid TumorMesothelioma, Malignant

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This trial tests a new drug (SW-682) for people with advanced solid tumors that have stopped responding to standard treatments. It focuses on cancers with specific gene changes (NF2 or Hippo pathway) and aims to see if the drug can shrink tumors or slow their growth.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
186 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have a solid cancer that has spread to other parts of the body or cannot be removed by surgery, and it has not responded to or stopped working after previous treatments.
  • Your cancer must be one of these types: mesothelioma, or a solid tumor with an NF2 mutation, or another change in the Hippo pathway (like FAT1, LATS1/2, YAP fusions, or WWTR1-CAMTA1).
  • You need to have a stored tumor sample from a previous biopsy or be willing to have a new biopsy taken for this study.
  • Your cancer must be measurable on scans (like CT or MRI).
  • You must be in fairly good health overall (able to do daily activities without help).
  • You cannot have active cancer spread to the brain causing symptoms, serious heart problems, or be taking medicines that interfere with the study drug.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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