Clin2
NCT06253754Possibly a fitRecruiting

Study of headache after spinal tap

Post-Dural Puncture Headache

Part of Brain & nervous system clinical trials.

This trial looks at why some people get a headache after a spinal tap and how treatment might help. It may be an option if you are between 20 and 40 and have this kind of headache.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
160 people
Ages
20 years to 40 years
Study type
Observational

Who can take part

  • You are between 20 and 40 years old.
  • You have a headache that gets worse when you sit or stand up (postural puncture headache).
  • You are not pregnant.
  • You do not have a pacemaker or other metal implants that are not safe for an MRI.
  • You have not had brain or spine surgery in the last year.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07354464Recruiting· Phase 3
Treating spinal headache: nose spray vs. blood patch

This trial compares two treatments for the severe headache that can occur after a spinal tap or epidural. One treatment is a numbing medicine sprayed into the nose (sphenopalatine block), the other is a blood patch (injecting your own blood into your back). The goal is to see which works better and faster.

Clermont-Ferrand
NCT07515456Recruiting
Comparing Three Medications for Spinal Headaches

This study tests three different medications—theophylline, sumatriptan, and gabapentin—to see which works best for headaches that occur after a spinal procedure. You would receive one of these treatments and be monitored to see how well it relieves your pain.

Tanta, El-Gharbia
NCT07436403Not yet recruiting
Comparing two ways to give spinal anesthesia for surgery

This trial tests two different ways to inject spinal anesthesia—through the middle or the side of the back—to see which causes fewer headaches afterward. If you're having orthopedic or urology surgery with spinal anesthesia, you may be able to join.

Lahore, Punjab Province
NCT05116930Recruiting· Phase 2
Medicine for headache after a labor spinal needle

This Phase 2 study tests neostigmine plus glycopyrrolate to treat a specific type of severe headache that happens after a dural puncture during labor. If you have a new headache starting within 72 hours of delivery and no other cause, this treatment may help relieve your pain.

Rochester, Minnesota
NCT05804448Recruiting
Altitude effect on spinal headache after C-section

This study looks at whether living at higher or lower altitudes changes the risk of a specific headache after a C-section done with spinal anesthesia. The goal is to understand who is more likely to get this headache so care can be better tailored.

Jumla, Karnali
NCT07729449Recruiting
Predicting headache after cesarean using ultrasound and oxygen monitoring

This trial measures how well two monitoring tools (optic nerve ultrasound and brain oxygen levels) can predict headache after a planned cesarean. It may help find better ways to prevent post-dural puncture headache.

Ordu, Altinordu

Hear when a new Post-Dural Puncture Headache trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.