Medications for eye pressure during breathing tube placement
Part of Brain & nervous system clinical trials.
This study tests how four different medications affect pressure inside the skull during the placement of a breathing tube for surgery. The medications are lidocaine, dexmedetomidine, esmolol, and magnesium—all commonly used to calm the body's response to intubation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 80 years old.
- Your physical status is ASA I, II, or III (generally healthy or with well-controlled medical conditions).
- You are not allergic to lidocaine, dexmedetomidine, esmolol, or magnesium.
- You do not have uncontrolled high blood pressure, advanced heart failure (ejection fraction below 35%), or certain heart rhythm problems.
- You do not have severe kidney or liver disease.
- You do not have a known brain condition or epilepsy.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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