Clinical trials
Intracranial Hypertension clinical trials
Below are recruiting intracranial hypertension clinical trials, each written for real people, not researchers. We’re tracking 21 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04032379Recruiting
Study biomarkers to predict outcomes in idiopathic intracranial hypertension
This study looks at body measurements (“biomarkers”) to help doctors diagnose idiopathic intracranial hypertension (IIH) and predict how it may go over time. If you’re an adult with a doctor’s concern for IIH, you may be asked to provide health information and possibly samples for testing.
Copenhagen, GlostrupAges 18 years+ - NCT06545981Recruiting
Eye blood flow in idiopathic intracranial hypertension
This study looks at how blood flows to the eyes in people with idiopathic intracranial hypertension (IIH), a condition where pressure builds up inside the skull. It compares these patients with healthy volunteers to better understand the disease and could lead to better treatments.
ViennaAges 18–90 - NCT06950099Recruiting
Advanced Brain Scans for IIH Patients Planning Stenting
This study uses advanced brain scans (MRIs) to look at the veins in your brain to help plan a stenting procedure for patients with Idiopathic Intracranial Hypertension (IIH) that is not improving with standard care.
Philadelphia, PennsylvaniaAges 18–55 - NCT07191873RecruitingPhase 4
Tirzepatide for treating high pressure in the brain
This trial tests if tirzepatide can help lower the pressure inside your skull caused by a condition called Idiopathic Intracranial Hypertension. It's designed for people with a BMI of 30 or higher who have swelling of the optic nerve.
Durham, North CarolinaAges 18–60 - NCT06919744Recruiting
Stenting for intracranial hypertension: early treatment study
This trial tests whether placing a small tube (stent) in a narrowed brain vein can help people with newly diagnosed intracranial hypertension (high pressure in the head) that causes vision problems. It is for those who have not yet taken standard medication and have specific vein narrowing seen on MRI.
MontpellierAges 18 years+ - NCT06855342Recruiting
Eye scans to check pressure inside the head
This study uses eye scans to see if changes in the retina can help doctors measure pressure inside the skull. It may help find a safer way to check for high pressure in the brain without needing a needle in the back.
London, LondonAges 18 years+ - NCT06945848Recruiting
Stenting for Intracranial Hypertension on Acetazolamide
This trial tests whether placing a stent (a small tube) in a narrowed brain vein can help reduce pressure in the head in people with Intracranial Hypertension who have been on acetazolamide for over a year. It may be an option if you still have high pressure despite medication.
MontpellierAges 18 years+ - NCT07332234Recruiting
Optic nerve ultrasound for brain inflammation and pressure
This study uses a quick ultrasound of the optic nerve to help doctors detect swelling or pressure in the brain. It may help people with suspected meningitis, encephalitis, stroke, or brain tumors decide on the best treatment earlier.
Bucharest, BucharestAges 18–60 - NCT06913712Recruiting
BMI and treatment response in IIH
This study looks at how body weight (BMI) affects how well people with Idiopathic Intracranial Hypertension (IIH) respond to treatment. It may help doctors understand if weight influences symptom relief.
Valencia, ValenciaAges 18 years+ - NCT04459806Recruiting
Study dose timing to improve care for brain injury
This trial studies how to time medication or treatment doses when a person has serious brain injury, using measurements from a pressure monitor in the skull. It may help doctors manage brain swelling and pressure more effectively.
Monza, MBAges 18–80 - NCT05707442RecruitingPhase 3
Stent or standard treatment for idiopathic intracranial hypertension
This Phase 3 trial compares putting in a venous sinus stent versus using medicine alone for idiopathic intracranial hypertension (IIH). It aims to see which approach better protects vision and lowers pressure in the brain.
Beijing, Beijing MunicipalityAges 18–60 - NCT06555900Recruiting
Predicting brain pressure spikes in injured patients using AI
This study is testing if an artificial intelligence program can predict dangerous increases in pressure inside the skull of people with brain injuries. If successful, it could help doctors treat these episodes sooner.
BrestAges 18–99 - NCT07420738Recruiting
Brain protection during heart bypass surgery study
This trial studies whether different circulatory support techniques during coronary artery bypass surgery affect blood flow to the brain. It may help find ways to protect brain function during the procedure.
IstanbulAges 18–75 - NCT05050864Recruiting
Stent versus brain-surgery options for idiopathic pressure
This study compares two treatment approaches for idiopathic intracranial hypertension (high pressure in the brain) that has not improved with usual medical treatment. It may help doctors learn which option works better and is safer for people with specific scan and eye findings.
Paris, ParisAges 18 years+ - NCT05340062Recruiting
Noninvasive brain-pressure check versus invasive test in children
This trial compares a noninvasive way to measure brain pressure to an invasive method in children. It may help reduce the need for painful or risky procedures while still getting useful measurements for care.
BolognaAges Up to 18 years - NCT05889650Recruiting
External drainage for severe TBI brain swelling
This study tests whether placing an external drainage tube in the lower back can reduce dangerous pressure in the brain after a severe traumatic brain injury. If you meet safety and brain-scan criteria, it may help the research team understand whether this approach is safe early after injury.
Gainesville, FloridaAges 18–65 - NCT06254534Recruiting
Medications for eye pressure during breathing tube placement
This study tests how four different medications affect pressure inside the skull during the placement of a breathing tube for surgery. The medications are lidocaine, dexmedetomidine, esmolol, and magnesium—all commonly used to calm the body's response to intubation.
IstanbulAges 18–80 - NCT06634069RecruitingPhase 2
Testing a new approach for septic shock patients
This trial tests a special fluid management strategy for people in septic shock—a serious infection that causes very low blood pressure. It aims to improve blood flow to organs and help you recover.
Pilsen, Czech RepublicAges 18–90 - NCT06928727Recruiting
Eye health in craniosynostosis study
This study looks at eye features in people with craniosynostosis (a condition where skull bones fuse too early). It may help doctors better understand eye problems that can occur with this condition.
AmiensAges Any age - NCT07440277Recruiting
Shunt vs. stent for IIH with vision loss risk
This study compares two treatments for Idiopathic Intracranial Hypertension (IIH) with severe papilledema (swollen optic nerves) and risk of vision loss: a CSF shunt (a tube to drain extra fluid) and a venous sinus stent (a mesh tube to open a narrowed vein). The goal is to see which works better and is more cost-effective.
BirminghamAges 18–63 - NCT07093151Enrolling by invitation
Comparing blood pressure goals after brain tumor surgery
This study looks at two different blood pressure targets after surgery to remove a brain tumor. The goal is to see which target helps patients recover better and have fewer complications.
Nashville, TennesseeAges 18 years+
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Common questions
- Are there clinical trials for intracranial hypertension?
- Yes. Clin2 currently lists 21 recruiting intracranial hypertension studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a intracranial hypertension trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a intracranial hypertension trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.