Clin2
NCT06275360Possibly a fitRecruiting

Immunotherapy re-treatment for veterans with lung cancer

Non-Small Cell Lung Cancer

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This trial tests whether restarting immunotherapy along with chemotherapy and radiation can help veterans with stage III lung cancer that cannot be removed by surgery. It's for people whose tumors have a certain protein (PD-L1) and who haven't had these treatments before for advanced cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
25 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are physically active enough to do daily activities (ECOG score 0 or 1).
  • Your lung cancer is stage III and cannot be removed surgically.
  • Your tumor tests positive for a protein called PD-L1 (at least 1%).
  • You have not had radiation to the chest or chemotherapy for advanced lung cancer before.
  • You do not have an autoimmune disease needing strong immune-suppressing drugs, active tuberculosis, hepatitis B or C, or HIV.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07146230Not yet recruiting· Phase 2
Personalized radiation and immunotherapy for advanced lung cancer

This trial tests giving radiation and immunotherapy together to people with advanced lung cancer that hasn't been treated yet. The goal is to see if this combination can shrink tumors and help patients live longer.

The Bronx, New York
NCT06388031Recruiting· Phase 2
Re-trying immunotherapy for advanced lung cancer after long-term success

This trial tests whether giving immunotherapy again can help people with advanced non-small cell lung cancer whose disease stayed stable for at least 2 years on their first immunotherapy but then started growing. It aims to see if a second course of treatment can work again.

Beijing
NCT06463665Recruiting· Phase 2
Virus therapy with chemo and immunotherapy for advanced lung cancer

This trial tests a new treatment that uses a virus to attack cancer cells, combined with standard chemotherapy and an immunotherapy drug, for people with advanced non-small cell lung cancer that has gotten worse after initial treatment. The goal is to see if this combination works better than a different chemotherapy drug alone.

Bullhead City, Arizona
NCT06561386Recruiting· Phase 3
Testing a new drug combo for advanced lung cancer

This trial is comparing a new combination of two immunotherapy drugs (nivolumab and relatlimab) plus chemotherapy against the standard immunotherapy (pembrolizumab) plus chemotherapy for people with advanced non-squamous non-small cell lung cancer that has a certain protein (PD-L1) on at least 1% of its cells. The goal is to see if the new combination works better.

Mobile, Alabama
NCT06448572Recruiting· Phase 1/Phase 2
EXL01 and nivolumab for immunotherapy-resistant lung cancer

This trial tests an investigational microbiome therapy (EXL01) combined with nivolumab (an immunotherapy) for people with advanced non-small cell lung cancer whose cancer continued to grow after standard immunotherapy and chemotherapy. The goal is to see if adding EXL01 can help the immune system fight the cancer again.

Lille
NCT06966583Not yet recruiting· Phase 1
NAD+ booster with radiation and immunotherapy for advanced lung cancer

This trial tests whether adding a NAD+ booster (NMN) to radiation and immunotherapy can help people with advanced lung cancer. It may improve the effectiveness of the treatment and help you live longer.

Chengdu, Sichuan

Hear when a new Non Small Cell Lung Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.