Comparing two heart-rate medicines for rapid atrial fibrillation or flutter
Part of Heart & circulation clinical trials.
This trial tests two medicines — one taken by mouth (bisoprolol) and one given through an IV (diltiazem) — to see which is better at safely slowing a too-fast heartbeat in people with atrial fibrillation or flutter. If you have this heart rhythm problem with a fast rate and are otherwise stable, the study might help find the most effective way to bring your heart under control.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have atrial fibrillation or flutter with a fast heart rate (more than 120 beats per minute) confirmed by an ECG.
- You feel stable (your blood pressure, oxygen, breathing, and consciousness are okay).
- You haven't taken any heart-rate-lowering medications (like beta-blockers, calcium channel blockers, digoxin, amiodarone) in the past 24 hours.
- You are not allergic to bisoprolol or diltiazem, not pregnant or breastfeeding, and have no severe liver or kidney problems.
- You don't have certain heart conditions (e.g., pre-excitation, recent heart attack, heart valve problems), known asthma, or recent use of stimulant drugs.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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