Colchicine for heart risk during major non-heart surgery
Treatments studied
Part of Heart & circulation clinical trials.
This study tests whether a low-cost, anti-inflammatory drug called colchicine can reduce heart complications after major non-heart surgery. If you have heart or blood vessel risk factors and are scheduled for a major operation, this trial may help protect your heart.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be having a major non-heart surgery (like belly, chest, spine, joint replacement, or certain types of blood vessel surgery).
- You must have at least one heart or blood vessel risk factor, such as past heart disease, stroke, high NT-proBNP, or a combination of older age, diabetes, high blood pressure, and others.
- You cannot have severe kidney disease (eGFR <30) or be on dialysis.
- You cannot have a known allergy or bad reaction to colchicine.
- You must not be pregnant, breastfeeding, or planning pregnancy.
- You cannot take certain medications (like cyclosporine, some antibiotics or heart meds) right after surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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