Colchicine for heart risk during major non-heart surgery
Treatments studied
Part of Heart & circulation clinical trials.
This study tests whether a low-cost, anti-inflammatory drug called colchicine can reduce heart complications after major non-heart surgery. If you have heart or blood vessel risk factors and are scheduled for a major operation, this trial may help protect your heart.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be having a major non-heart surgery (like belly, chest, spine, joint replacement, or certain types of blood vessel surgery).
- You must have at least one heart or blood vessel risk factor, such as past heart disease, stroke, high NT-proBNP, or a combination of older age, diabetes, high blood pressure, and others.
- You cannot have severe kidney disease (eGFR <30) or be on dialysis.
- You cannot have a known allergy or bad reaction to colchicine.
- You must not be pregnant, breastfeeding, or planning pregnancy.
- You cannot take certain medications (like cyclosporine, some antibiotics or heart meds) right after surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether the drug colchicine can reduce inflammation and protect organs during and after planned heart surgery. It may help people recover better.
This trial tests whether taking colchicine around the time of surgery can reduce bad events after surgery in people at higher heart risk. It focuses on helping prevent complications related to inflammation after an operation.
This trial tests whether the drug colchicine can reduce inflammation after planned coronary artery bypass graft (CABG) surgery. It may help patients recover better by lowering inflammatory markers.
This trial tests whether the drug colchicine can reduce the chance of developing atrial fibrillation (an irregular heart rhythm) after open-heart surgery. If it works, it could help you recover more smoothly.
This trial tests whether colchicine (a medicine used for gout) can help prevent heart problems after a stent procedure (PCI). It's for people who are in the hospital getting a stent and follow standard heart care.
This trial tests whether a low dose of the anti-inflammatory drug colchicine can help people who have recently had a heart attack or unstable angina. It aims to see if colchicine reduces the risk of future heart problems.
Hear when a new Cardiovascular Diseases trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.