Colchicine’s effect on inflammation after heart bypass surgery
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether the drug colchicine can reduce inflammation after planned coronary artery bypass graft (CABG) surgery. It may help patients recover better by lowering inflammatory markers.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- You are scheduled to have planned (not emergency) coronary artery bypass graft (CABG) surgery.
- You do not have a history of atrial fibrillation.
- You are not currently taking colchicine, and you have no known allergy to colchicine.
- You do not have severe liver, kidney, muscle, or intestinal disease, and you are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether taking a low dose of colchicine, an anti-inflammatory medicine, after heart bypass surgery can help keep the new blood vessels open and working well. It may help reduce the chance of the bypass grafts failing.
This study tests whether a low dose of colchicine, an anti-inflammatory drug, can help prevent the graft (new blood vessel) from failing after heart bypass surgery. It's for people who just had a bypass and are still in the hospital.
This trial tests whether a low dose of the anti-inflammatory drug colchicine can help people who have recently had a heart attack or unstable angina. It aims to see if colchicine reduces the risk of future heart problems.
This study tests whether the drug colchicine can reduce inflammation and protect organs during and after planned heart surgery. It may help people recover better.
This study tests whether taking colchicine (a common anti-inflammatory medication) before and after bypass heart surgery can prevent atrial fibrillation—an irregular heartbeat that sometimes occurs after surgery. Researchers hope this simple treatment might reduce complications and improve recovery.
This trial tests whether taking colchicine around the time of surgery can reduce bad events after surgery in people at higher heart risk. It focuses on helping prevent complications related to inflammation after an operation.
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