Colchicine’s effect on inflammation after heart bypass surgery
Treatments studied
Part of Heart & circulation, Immune system & allergy clinical trials.
This trial tests whether the drug colchicine can reduce inflammation after planned coronary artery bypass graft (CABG) surgery. It may help patients recover better by lowering inflammatory markers.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- You are scheduled to have planned (not emergency) coronary artery bypass graft (CABG) surgery.
- You do not have a history of atrial fibrillation.
- You are not currently taking colchicine, and you have no known allergy to colchicine.
- You do not have severe liver, kidney, muscle, or intestinal disease, and you are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether the drug colchicine can reduce the chance of developing atrial fibrillation (an irregular heart rhythm) after open-heart surgery. If it works, it could help you recover more smoothly.
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This study tests whether a low dose of colchicine, an anti-inflammatory drug, can help prevent the graft (new blood vessel) from failing after heart bypass surgery. It's for people who just had a bypass and are still in the hospital.
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This trial tests whether a low dose of the anti-inflammatory drug colchicine can help people who have recently had a heart attack or unstable angina. It aims to see if colchicine reduces the risk of future heart problems.
This trial tests if colchicine, an anti-inflammatory medicine, can help people with a type of heart failure where the heart pumps well but is stiff and inflamed. You may join if your heart failure recently worsened and you have signs of inflammation in your blood.
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