Testosterone treatment for boys with Klinefelter syndrome in puberty
Treatments studied
Part of Genetic & congenital, Hormones & metabolism, Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial tests if starting testosterone treatment during puberty (ages 10-14) helps boys with Klinefelter syndrome. It aims to understand how the hormone affects development and well-being.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with Klinefelter syndrome (47,XXY).
- You are between 10 and 14 years old.
- Your luteinizing hormone level is higher than normal for your age.
- Your free testosterone level is normal or slightly low.
- Your parents have signed a consent form to allow you to take part.
- You have not had testosterone treatment before (except for a very short course in infancy).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study follows patients with Klinefelter syndrome over time to learn more about their health. It may help doctors better understand and care for people with this condition.
This study tests whether adjusting sex-hormone levels can improve body metabolism and reproductive hormone balance in people with Klinefelter syndrome. Depending on the design, you may be looking at fertility preservation and/or metabolic health.
This study looks at how the thyroid gland works and how it looks on ultrasound in people with classic (non-mosaic) 47,XXY Klinefelter syndrome. It may help doctors understand thyroid-related problems in this condition by comparing test results, symptoms, and imaging.
This trial tests a testosterone injection (XYOSTED) to see if it's safe and effective for replacing testosterone in teenage boys who have low levels due to a known medical condition. It lasts 52 weeks, with an optional 2-year follow-up.
This trial tests an experimental medicine for teenage boys with a condition called hypogonadotropic hypogonadism, where the body doesn't make enough sex hormones. The treatment combines two hormone-based injections to help the testes grow and function, with a goal of improving puberty.
This trial tests a new testosterone gel at different doses to see how it affects men with low testosterone (below 300 ng/dL). It aims to find the right dose that safely and effectively raises testosterone levels in men aged 18-75.
Hear when a new Klinefelter Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.