Pacing and ablation for heart failure with atrial fibrillation
Part of Heart & circulation clinical trials.
This trial tests a special way to pace the heart and a procedure to quiet the irregular rhythm in people with advanced heart failure and long-standing atrial fibrillation. It may help improve symptoms and heart function, possibly reducing the need for a transplant.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 19 or older.
- You have an implantable defibrillator (ICD) or are a candidate for one.
- You've had atrial fibrillation (irregular heartbeat) for over 6 months, and catheter ablation didn't work or isn't an option.
- Your heart failure is advanced, and you're being considered for a heart transplant or a mechanical heart pump (LVAD).
- Your heart's pumping ability is low (LVEF of 35% or less).
- You've been on optimal heart failure medications for at least 3 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if a pacemaker plus an ablation procedure can improve heart failure symptoms in people with atrial fibrillation. It is for those with moderate to severe heart failure who are already on the right medications.
This trial compares two types of pacing for people with permanent atrial fibrillation (AF) and a weak heart pump (ejection fraction less than 50%). It tests whether pacing the left bundle branch area works as well as or better than standard biventricular pacing to improve heart function.
This study compares two treatments for people with atrial fibrillation and heart failure: one is a procedure to fix the irregular heartbeat (AF ablation), and the other involves a different type of pacing for the heart. It aims to find which approach helps you feel better and stay out of the hospital.
This trial tests whether a catheter procedure that treats atrial fibrillation works better than standard care for people with heart failure with preserved ejection fraction. It aims to improve heart rhythm symptoms and overall outcomes compared with conventional treatment.
This study tests a new way to pace the heart (using a specific spot called the Bachmann bundle) to prevent new episodes of atrial fibrillation (an irregular heartbeat) in people with heart failure who already need a pacemaker or defibrillator. The goal is to keep the heart's rhythm more stable and reduce the risk of future heart rhythm problems.
This study tests a new approach called 'Ablate and Pace HIS' for people with atrial fibrillation and heart failure who haven't improved with other treatments. It combines a heart ablation procedure with a special type of pacing to help your heart pump more efficiently and reduce symptoms.
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