Comparing heart treatments for atrial fibrillation and heart failure
Part of Heart & circulation clinical trials.
This study compares two treatments for people with atrial fibrillation and heart failure: one is a procedure to fix the irregular heartbeat (AF ablation), and the other involves a different type of pacing for the heart. It aims to find which approach helps you feel better and stay out of the hospital.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have persistent atrial fibrillation (a long-lasting irregular heartbeat) and symptoms of heart failure even with medication.
- In the past 2 years, you had at least one hospital stay or emergency visit for heart failure, and a blood test showed high NT-pro-BNP or BNP levels.
- You are over 60 years old, and you are currently taking or have taken medications to control your heart rate or rhythm.
- You have not had a prior atrial fibrillation ablation procedure more than once.
- You do not have severe heart failure that keeps you at rest with very low blood pressure, a life expectancy less than 2 years, or recent heart attacks or strokes.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two procedures for people who have both atrial fibrillation (AFib) and heart failure: one that slows the heart's electrical signals (AV node ablation) and one that helps the heart pump in a more coordinated way (cardiac resynchronization). Both are options when medications alone aren't enough, and the goal is to improve symptoms and quality of life.
This trial tests whether a procedure that regulates your heart rhythm (pacing) works better than medication for people who have permanent atrial fibrillation, heart failure with a normal pumping strength, and were hospitalized for heart failure in the past year.
This trial studies whether a strategy to regularize (control) heart rate can improve outcomes in people who have permanent atrial fibrillation and heart failure. It focuses on people with recent heart-failure hospitalization and checks several heart, kidney, and health-condition limits to keep the study safe.
This trial tests if a pacemaker plus an ablation procedure can improve heart failure symptoms in people with atrial fibrillation. It is for those with moderate to severe heart failure who are already on the right medications.
This study looks at whether a “rate control” or “rhythm control” approach works better for people with CRT devices who still have atrial fibrillation. It aims to improve heart failure symptoms and help the heart pace more effectively.
This study compares two treatments for people with atrial fibrillation (an irregular heartbeat) and a specific type of heart failure. It looks at whether a procedure called catheter ablation (which uses heat to fix the heart's rhythm) works better than taking daily heart rhythm medications.
Hear when a new Heart failure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.