Clin2
NCT06304389Possibly a fitRecruiting

Blue light therapy for epilepsy with vagus nerve stimulation

Refractory Epilepsy

Part of Brain & nervous system clinical trials.

This trial tests if blue light exposure can improve the effects of vagus nerve stimulation (VNS) in people with epilepsy that is hard to control. It also includes some healthy volunteers for comparison. The goal is to find new ways to make VNS work better.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
34 people
Ages
18 years to 60 years
Study type
Interventional

Who can take part

  • You must have a vagus nerve stimulator (VNS) implanted for at least 3 months.
  • You are between 18 and 60 years old.
  • Your IQ is above 55 (normal or mildly impaired cognitive ability).
  • If you are healthy, you must be between 18 and 35 years old with no neurological or psychiatric conditions.
  • You cannot have any other implanted medical devices (like a pacemaker) or eye diseases.
  • You cannot have a history of brain injury.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04935567Not yet recruiting
Predicting vagus nerve stimulation success in drug-resistant epilepsy

This study looks at whether a brain wave test can help predict how well vagus nerve stimulation (VNS) will work for people with epilepsy that hasn't been controlled by medication. VNS is a treatment that uses a device to send mild electrical signals to the brain to reduce seizures.

Brno
NCT06038929Recruiting
Vagus nerve stimulation and stomach function study

This study looks at how vagus nerve stimulation (VNS) affects how your stomach works, like emptying and stretching. It may help researchers understand the digestive side effects of VNS in people who already have a VNS device for epilepsy or depression.

Minneapolis, Minnesota
NCT03953768Recruiting
Testing a new vagus nerve stimulator for gut and immune health

This study looks at what happens to your immune system and stomach/gut function after getting a vagus nerve stimulator (VNS) for the first time for epilepsy. It may help doctors understand whether the device benefits more than seizures.

Louisville, Kentucky
NCT06016686Recruiting· Phase 1
Recording nerve signals from the vagus nerve in awake humans

This study tests a new way to listen to the vagus nerve in awake people. It may help understand how the nerve controls body functions like heart rate and digestion.

Minneapolis, Minnesota
NCT06334952Recruiting
Personalized brain stimulation for hard-to-treat epilepsy

This study tests a personalized, non-invasive brain stimulation method called tDCS for people with drug-resistant epilepsy that starts in one part of the brain. It aims to reduce seizures in those who cannot have surgery or have not been helped by surgery.

Bordeaux
NCT05664854Recruiting
Vagus nerve stimulation guided by body imaging

This study uses a painless body scan method (electrical impedance imaging) and a targeted vagus nerve stimulation to see if it helps people with conditions that might respond to this kind of nerve treatment. If you may benefit from vagus nerve stimulation, this trial may help doctors learn whether the approach is effective and safe for you.

London, Greater London

Hear when a new Refractory Epilepsy trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.