Studying a very low calorie keto diet for fatty liver disease with scarring
Part of Digestive system, Hormones & metabolism clinical trials.
This trial tests whether a very low calorie ketogenic diet (a strict low-carb, high-fat diet) can help people with non-alcoholic steatohepatitis (NASH) who have liver scarring. Participants will follow this diet for a year and have two liver biopsies to see if their liver health improves.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older and have been diagnosed with NASH and some liver scarring in the last 6 months.
- Your weight has been steady for at least 6 months and your body mass index (BMI) is between 30 and 40.
- You are willing to have a liver biopsy at the start and after 12 months to check the diet's effect.
- You do not have cirrhosis (advanced liver scarring) or other serious liver diseases.
- You do not have type 1 diabetes, and your blood tests (like liver enzymes and kidney function) are within safe limits.
- You have not had recent weight loss surgery, a liver transplant, or taken certain medications that affect the liver.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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