Clinical trials
NAFLD clinical trials
Below are recruiting nafld clinical trials, each written for real people, not researchers. We’re tracking 89 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07093346Recruiting
Pectin supplement for fatty liver disease
This study tests whether a pectin supplement (a fiber found in fruits) can reduce inflammation and improve liver and metabolic health in people with fatty liver disease (MASLD). You might be eligible if you have MASLD, a healthy weight range, and can avoid certain medications and foods.
NottinghamAges 18 years+ - NCT07241195Recruiting
Fatty Liver Study in Older Adults
This study follows older adults with fatty liver disease to understand how their metabolism changes over time and how it affects their overall health. It helps researchers learn more about the condition and its impact on the body outside the liver.
Hangzhou, ZhejiangAges 65–100 - NCT04634643Recruiting
Studies what causes fatty liver in teens
This study looks at why “nonalcoholic fatty liver disease” happens in teenagers and how it develops. It may help doctors better predict and prevent liver problems in children, even if there isn’t a new drug for you to take.
New Haven, ConnecticutAges 12–18 - NCT04036357Recruiting
Study of liver fat disease with heart and metabolism problems
This study looks at people with fatty liver disease and common health issues like obesity, diabetes, high blood pressure, or abnormal cholesterol. It may help researchers understand how liver fat and heart/metabolism problems relate and how they affect health over time.
RomeAges 18–80 - NCT04442334Recruiting
European registry for people with fatty liver
This registry collects health and lifestyle information from adults with suspected or confirmed fatty liver (NAFLD) to help researchers better understand the condition. You may be asked about diet, exercise, alcohol intake, and some liver-related tests.
AntwerpAges 18–100 - NCT04681573Recruiting
Tests two non-invasive ways to check liver scarring
This study compares two non-invasive approaches to diagnose advanced liver scarring in people with non-alcohol-related fatty liver disease (NAFLD). It may help confirm which test strategy finds advanced scarring without needing a biopsy for everyone.
AngersAges 18–80 - NCT05477212Recruiting
Study gut leakiness in obesity and fatty liver with a ketogenic diet
This study looks at “gut permeability,” sometimes called intestinal leakiness, in people with obesity and fatty liver disease. It tests whether a ketogenic (very low-carb) diet changes gut leakiness and fatty liver measurements.
Castellana Grotte, BARIAges 18–65 - NCT05618626Recruiting
Lifestyle program to prevent fatty liver and heart disease
This trial tests whether a structured lifestyle program—focused on healthy living and resistance exercise—can help prevent fatty liver disease and heart-related problems. It may be helpful if you have early or mild fatty liver changes or risk factors, even if you also have gallstones.
Molina, Maule RegionAges 45–60 - NCT05816915Recruiting
Lifestyle changes for fatty liver with metabolic health issues
This trial studies whether a lifestyle program can improve fatty liver disease in people who also have metabolic syndrome (a cluster of health problems like high blood sugar and cholesterol). It may help by improving liver health through diet, activity, and other lifestyle changes.
PragueAges 18 years+ - NCT05930093Recruiting
Test LivPhcD capsules for fatty liver disease safety
This trial studies whether LivPhcD capsules can improve fatty liver disease and checks for side effects. It may help people with non-alcohol-related fatty liver disease who meet specific liver-scanning and lab results.
Taipei, Not Required For This CountryAges 20–75 - NCT05979389RecruitingPhase 1
Bicalutamide for young women with PCOS and fatty liver
This trial tests a medicine called bicalutamide (an anti-androgen) to see if it can help young women with both PCOS and fatty liver disease (NASH). The goal is to find a new treatment option for these two conditions together.
San Francisco, CaliforniaAges 18–42 - NCT06098417Recruiting
Fatty liver markers before weight-loss surgery
This study looks at special markers in the blood to better understand and predict a fatty liver condition called NAFLD. It focuses on people who are very overweight and are already planning to have weight-loss surgery.
TriesteAges 18–65 - NCT06124261Recruiting
Hormones and fatty liver study
This study looks at how hormones (androgens) relate to fatty liver disease (MASH) in women, especially those with PCOS. It aims to understand why some women develop worse liver problems and might help find new ways to treat or prevent them.
San Francisco, CaliforniaAges 18–42 - NCT06124456Recruiting
Vigorous vs. moderate exercise for liver fat reduction
This study compares high-intensity exercise to moderate-intensity exercise to see which is better at reducing fat in the liver for people with obesity and fatty liver disease.
Hong KongAges 18–69 - NCT06186869Recruiting
Diet and exercise for fatty liver disease
This study tests whether combining diet with two different exercise programs can help people who are overweight or obese and have fatty liver disease. The goal is to see which program works best to reduce liver fat and improve health.
Castellana Grotte, BariAges 18–65 - NCT06445361Recruiting
Liver fat study in type 1 diabetes
This trial looks at how common fatty liver disease is in people with type 1 diabetes. Doctors will check your liver with tests to learn more and find out if you might be at risk.
Genk, LimburgAges 18 years+ - NCT06477146RecruitingPhase 2
Milk thistle for fatty liver in children and young adults
This trial tests whether milk thistle can help children and young adults with non-alcoholic fatty liver disease (NAFLD), a condition where fat builds up in the liver unrelated to alcohol use. It aims to see if the supplement can lower liver enzymes and improve liver health.
Cleveland, OhioAges 9–22 - NCT06503068Recruiting
Liver disease name stigma and quality of life study
This study looks at how the names of two liver conditions (NAFLD and MAFLD) affect how patients feel about their illness and their quality of life. If you have NAFLD or NASH, you can help by filling out a survey.
Tanta, GharbyeaAges 18 years+ - NCT06591169Recruiting
Lifestyle changes for PCOS, sleep apnea, and fatty liver
This trial studies whether making lifestyle changes (like diet and exercise) can help women who have PCOS, sleep apnea, and fatty liver disease. It aims to see if these changes can improve their health and reduce symptoms.
Dokki, Giza GovernorateAges 30–40 - NCT06671886Recruiting
NAFLD care pathway for veterans
This trial tests a new care pathway for non-alcoholic fatty liver disease (NAFLD) in veterans. It aims to improve how patients are diagnosed and treated through their primary care team.
Houston, TexasAges 18 years+ - NCT06694935RecruitingPhase 1
Testing QX1206 in type 2 diabetes with fatty liver
This trial tests a new pill called QX1206 for people who have both Type 2 diabetes and fatty liver disease (NAFLD). The goal is to see if the medicine is safe and can help improve both conditions.
TorontoAges 18–64 - NCT07128797RecruitingPhase 1
Safety and tolerability of B1344 injections for NAFLD
This trial tests whether multiple injections of B1344 are safe and tolerable in people with nonalcoholic fatty liver disease (NAFLD). It aims to find the right dose and check how the drug works in the body.
Beijing, Beijing MunicipalityAges 18–75 - NCT05699018Recruiting
Screening people with liver scarring in primary care
This study tests how well primary care doctors can screen for advanced liver scarring in people with fatty liver from non-alcohol causes or from alcohol use. It may help find liver problems earlier so you can get the right follow-up.
AngersAges 40–80 - NCT07518784Recruiting
Testing a new liver scanning device for fatty liver disease
This study tests a new device called LiverScope® that scans your liver to detect fatty liver disease (MASLD). The scan uses special imaging technology and may help doctors diagnose liver disease more quickly and accurately.
La Jolla, CaliforniaAges 18 years+
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NAFLD trials by city
Studies with a site in or near these metro areas.
NAFLD trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for nafld?
- Yes. Clin2 currently lists 89 recruiting nafld studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a nafld trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a nafld trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.