Clemastine and exercise for thinking problems in schizophrenia
Part of Mental health clinical trials.
This study tests whether a common antihistamine (clemastine) combined with aerobic exercise can improve memory and thinking problems in people with schizophrenia. It aims to help the brain's myelin repair and may offer a new treatment option for cognitive symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 65 years old and have a diagnosis of schizophrenia or a related disorder.
- Your psychiatric medications (like antipsychotics or mood stabilizers) need to be at a stable dose for at least a week before starting the study.
- You should not have an active moderate or severe substance use disorder (other than nicotine).
- Women who can become pregnant must use effective birth control and have a negative pregnancy test.
- You must not have certain medical conditions like epilepsy, glaucoma, or severe liver/kidney problems, and you cannot be taking certain other medications.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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