Clin2
NCT06316427Possibly a fitRecruiting

CD7 CAR-T therapy for T-cell cancers that returned

T-cell Acute Lymphoblastic LeukemiaAcute Lymphoblastic Leukemia, in RelapseRefractory Acute Lymphoblastic LeukemiaT-cell Malignancies

Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.

This trial tests a new kind of immunotherapy called CD7 CAR-T therapy for people with T-cell cancers (like leukemia or lymphoma) that have come back or not responded to treatment. The CAR-T cells are made from your own immune cells or a donor's, and they are designed to find and destroy cancer cells that carry the CD7 marker.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
80 people
Ages
1 year to 70 years
Study type
Interventional

Who can take part

  • Your cancer must be a type of T-cell cancer that has the CD7 marker on the cancer cells.
  • You must have already tried all standard treatments (like chemo or a stem cell transplant) and they didn't work or you couldn't tolerate them.
  • You are between 1 and 70 years old.
  • You are generally able to care for yourself (ECOG score 0–2) and your doctor thinks you have at least 2 months to live.
  • You do not have severe heart, lung, kidney, or liver failure, uncontrolled infections, other cancers, or serious mental health conditions.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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