Device removal vs full medical treatment for infected heart devices
Part of Infections clinical trials.
This trial compares removing a heart device (like a pacemaker) versus using antibiotics and other medical care to treat an infection. It may help doctors decide the best way to handle infections related to these devices.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a possible infection in your heart device (pacemaker or defibrillator).
- You have a bloodstream infection caused by certain bacteria or fungi (e.g., Staphylococcus aureus or Candida).
- Or you have an infection on a heart valve on the left side of your heart.
- You are available for follow-up visits and willing to sign a consent form.
- You are not too frail (score less than 7 on a clinical frailty scale).
- Your surgical risk is not too high (EUROSCORE II ≤33%) and your lung function is adequate (FEV1 ≥1 liter or ≥30% of expected).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies whether people with an implanted heart device infection should take antibiotics for life or stop antibiotics and monitor closely. It is for situations where doctors think removing the device is not a safe or suitable option.
This trial tests if a new, faster approach to replacing an infected pacemaker or defibrillator is safe. If you have a heart device infection and meet recovery milestones, you might be able to get a new device sooner than usual.
This study is testing an approach to improve how clinicians care for people with suspected infections around an implanted heart device (like a pacemaker or defibrillator). It may help ensure the infection is recognized and treated appropriately, especially when device removal (extraction) might be needed.
This trial tests whether a shorter course of antibiotics is as safe and effective as the standard longer course for people who have had an infected heart device removed. It aims to reduce side effects and make treatment easier.
This study looks at the long-term health of people who had an infected heart device (pacemaker or defibrillator) removed. It helps doctors understand what happens years after the removal, so they can better care for others in the future.
This trial compares taking antibiotics by mouth versus receiving antibiotics through a vein (outpatient IV) for an infection of the heart valve. It’s designed to see whether the oral option can work as well and safely, especially after initial treatment and surgery if needed.
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