Atorvastatin plus temozolomide for EGFR-positive glioblastoma
Treatments studied
Part of Cancer clinical trials.
This trial tests whether adding the cholesterol drug atorvastatin to the standard chemotherapy temozolomide improves outcomes for people with a specific type of glioblastoma (brain cancer) that is positive for the EGFR protein. It aims to find a more effective treatment for this aggressive tumor.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 60 years old.
- Your tumor must be a type of brain cancer called glioblastoma (WHO grade 4) and be positive for a protein called EGFR (score 3).
- You must have normal blood counts and liver function, and be otherwise healthy enough for treatment.
- You cannot be allergic to atorvastatin (a cholesterol drug) or take certain other medicines that interact with it.
- You cannot have another cancer, a serious infection, or be pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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