Pioglitazone for pulmonary hypertension from lung disease
Treatments studied
Part of Heart & circulation, Lungs & breathing clinical trials.
This trial tests if pioglitazone, a medicine used for diabetes, can help people with high blood pressure in their lungs caused by chronic lung disease. The goal is to see if it improves how your cells use energy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have high blood pressure in your lungs (pulmonary hypertension) caused by chronic lung disease, confirmed by a heart catheter test.
- Your pulmonary hypertension medicines must be at the same dose for at least 30 days before starting.
- You cannot have diabetes (type 1 or type 2) now or in the past year.
- You cannot have used pioglitazone, rosiglitazone, metformin, insulin, or other diabetes medicines in the last 90 days.
- You cannot have a history of bladder cancer or low platelet counts (≤120).
- You cannot currently smoke or have cystic fibrosis.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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